LASER: Large genome ASsembly EvaluatoR
نویسندگان
چکیده
منابع مشابه
Comparative genome assembly
One of the most complex and computationally intensive tasks of genome sequence analysis is genome assembly. Even today, few centres have the resources, in both software and hardware, to assemble a genome from the thousands or millions of individual sequences generated in a whole-genome shotgun sequencing project. With the rapid growth in the number of sequenced genomes has come an increase in t...
متن کاملMaximum Likelihood Genome Assembly
Whole genome shotgun assembly is the process of taking many short sequenced segments (reads) and reconstructing the genome from which they originated. We demonstrate how the technique of bidirected network flow can be used to explicitly model the double-stranded nature of DNA for genome assembly. By combining an algorithm for the Chinese Postman Problem on bidirected graphs with the constructio...
متن کاملGenome Assembly Techniques
Title of thesis: GENOME ASSEMBLY TECHNIQUES Guillaume Marçais, Doctor of Philosophy, 2011 Thesis directed by: James Yorke and Carl Kingsford Since the publication of the human genome in 2001, the price and the time of DNA sequencing have dropped dramatically. The genome of many more species have since been sequenced, and genome sequencing is an ever more important tool for biologists. This tren...
متن کاملUser Evaluator Simplifier
Solving sophisticated mathematical problems often requires algebraic algorithms and theorems. However, there are no environments integrating theorem provers and computer algebra systems which consistently provide the inference capabilities of the rst and the powerful arithmetic of the latter systems. As an example for such a mechanized mathematics environment we describe a prototype implementat...
متن کاملGenome Assembly Analytics with Hawkeye
We present here Hawkeye, a visual analytics platform for genome assembly analysis and validation. Hawkeye blends the best practices from information and scientific visualization to facilitate human inspection of large-scale assembly data while minimizing the time needed to detect mis-assemblies and make effective judgments. All levels of the assembly data hierarchy are made accessible to users,...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMC Research Notes
سال: 2015
ISSN: 1756-0500
DOI: 10.1186/s13104-015-1682-y